Table 2.
Proteins specifically involved in lactate metabolism are significantly more abundant during growth on lactate relative to growth on proline betaine
| Name | Accession number | Function | Percentage of total detected protein in proline betaine–grown cells | Percentage of total detected protein in lactate-grown cells | -Fold change (lactate/proline betaine) | p value |
|---|---|---|---|---|---|---|
| mol % | mol % | -fold | ||||
| LctA | WP_052237246.1 | Transcriptional regulator | 0.0013 ± 0.00062 | 0.0038 ± 0.0017 | 2.9 | 0.036 |
| LctB | WP_038352354.1 | Electron transfer flavoprotein subunit β | 0.00013 ± 0.00026 | 2.1 ± 0.96 | 16,000 | 0.0053 |
| LctC | WP_038352355.1 | Electron transfer flavoprotein subunit α | NDa | 2.4 ± 0.86 | 0.0013 | |
| LctD | WP_013380257.1 | Lactate dehydrogenase | ND | 1.9 ± 0.566 | 0.00061 | |
| LctE | WP_038352356.1 | Lactate permease | ND | 0.0029 ± 0.00082 | 0.00041 | |
| LctF | WP_038352908.1 | Lactate racemase | 0.0039 ± 0.00086 | 0.23 ± 0.11 | 59 | 0.0057 |
| PorA | WP_038354167.1 | Pyruvate:ferredoxin oxidoreductase | 0.16 ± 0.03 | 2.3 ± 1.2 | 14 | 0.01 |
a ND, not detected.