Table 2. Adjusted AUROCs and comparisons for prediction of hospital mortality outcomes.
| Outcome | SIRS | qSOFA | NEWS | SOFA |
|---|---|---|---|---|
|
Mortality (N = 10942) AUROC (95% CI) |
0.79 (0.78–0.81) | 0.84 (0.83–0.85) | 0.85 (0.84–0.86) | 0.90 (0.89–0.91) |
| vs. SIRS | <0.001 | <0.001 | <0.001 | |
| vs. qSOFA | <0.001 | <0.001 | <0.001 | |
| vs. NEWS | <0.001 | <0.001 | <0.001 | |
| vs. SOFA | <0.001 | <0.001 | <0.001 | |
|
ICU Mortality (n = 3749) AUROC (95% CI) |
0.68 (0.66–0.70) | 0.68 (0.66–0.70) | 0.70 (0.68–0.72) | 0.82 (0.80–0.83) |
| vs. SIRS | 0.84 | 0.03 | <0.001 | |
| vs. qSOFA | 0.84 | 0.003 | <0.001 | |
| vs. NEWS | 0.03 | 0.003 | <0.001 | |
| vs. SOFA | <0.001 | <0.001 | <0.001 | |
|
Non-ICU Mortality (n = 7193) AUROC (95% CI) |
0.81 (0.78–0.84) | 0.84 (0.80–0.87) | 0.84 (0.81–0.88) | 0.86 (0.83–0.89) |
| vs. SIRS | 0.08 | 0.01 | 0.004 | |
| vs. qSOFA | 0.08 | 0.26 | 0.13 | |
| vs. NEWS | 0.01 | 0.26 | 0.38 | |
| vs. SOFA | 0.004 | 0.13 | 0.38 |
Abbreviations: AUROC, area under the receiver operator curve; CI, confidence interval; ICU, intensive care unit; NEWS, national early warning score; qSOFA, quick sequential organ failure assessment; SIRS, systemic inflammatory response syndrome; SOFA, sequential organ failure assessment. N values correspond to the number of patients included in the analysis who were eligible to experience the outcome.