Table 2.
Differences in behavior by sex and HPV16 and HPV18 L1 seroprevalence. Bolding indicates statistical significance. IQR, interquartile range.
| Men n(%) | Women n(%) | p-value | HPV16 (+) n(%) | HPV16 (-) n(%) | p-value | HPV18 (+) n(%) | HPV18 (-) n(%) | p-value | |
|---|---|---|---|---|---|---|---|---|---|
| 281 (75) | 93 (25) | 21 (6) | 353 (94) | 17 (5) | 357 (95) | ||||
| Sexual Exposure | |||||||||
| First sexual act as: | |||||||||
| Oral sex | 39 (15) | 8 (9) | 0.14 | 2 (10) | 45 (14) | 1.0 | 2 (12) | 45 (13) | 1.0 |
| Oral sex on a woman | 32 (12) | 1 (1) | 0.001 | 0 (0) | 33 (10) | 0.24 | 0 (0) | 33 (10) | 0.38 |
| Oral sex on a man | 8 (3) | 7 (8) | 0.06 | 2 (10) | 13 (4) | 0.21 | 2 (12) | 13 (4) | 0.14 |
| Vaginal sex | 189 (74) | 67 (80) | 0.30 | 13 (68) | 243 (76) | 0.46 | 11 (73) | 245 (76) | 0.77 |
| Vaginal sex with a woman | 189 (74) | 0 (0) | <0.001 | 7 (37) | 182 (57) | 0.09 | 6 (40) | 183 (56) | 0.21 |
| Vaginal sex with a man | 0 (0) | 67 (81) | <0.001 | 6 (32) | 61 (19) | 0.18 | 5 (33) | 62 (19) | 0.18 |
| Lifetime sexual partners, median (IQR): | |||||||||
| Any | 8 (3–19) | 5 (2–13) | 0.31 | 9 (4–23) | 7 (3–15) | 0.22 | 9 (5–20) | 6 (3–15) | 0.11 |
| Oral | 4 (1–8) | 2 (1–4) | 0.005 | 4 (2–13) | 3 (1–7) | 0.004 | 5 (2–10) | 3 (1–7) | 0.006 |
| Vaginal | 7 (3–15) | 5 (2–12) | 0.08 | 8 (4–15) | 6 (3–15) | 0.98 | 8 (4–15) | 6 (2–15) | 0.98 |
| Open mouth kissing | 10 (5–23) | 8 (3–20) | 0.10 | 15 (5–35) | 10 (4–20) | 0.48 | 15 (6–30) | 10 (4–20) | 0.10 |
| Recent sexual partners, median (IQR): | |||||||||
| Any | 1 (0–1) | 1 (0–1) | 0.41 | 1 (0–2) | 1 (0–1) | 0.17 | 1 (0–1) | 1 (0–1) | 0.24 |
| Oral | 1 (0–1) | 0 (0–1) | 0.07 | 1 (0–2) | 1 (0–1) | <0.001 | 1 (0–1) | 1 (0–1) | 0.002 |
| Vaginal | 1 (1–1) | 1 (0–1) | 0.03 | 1 (1–1) | 1 (0–1) | 0.76 | 1 (0–1) | 1 (0–1) | 0.47 |
| Homosexual/Bisexual/Other | 17 (7) | 11 (12) | 0.09 | 24 (7) | 4 (20) | 0.06 | 4 (25) | 24 (7) | 0.03 |
| History of genital warts | 13 (5) | 4 (4) | 1.0 | 1 (5) | 16 (5) | 1.0 | 1 (7) | 16 (5) | 0.53 |
| Coitarche at <18 years | 124 (48) | 28 (32) | 0.008 | 8 (40) | 144 (45) | 0.69 | 5 (31) | 147 (45) | 0.28 |
| Relationship status | |||||||||
| Widowed/divorced/separated | 0.01 | 0.10 | 0.84 | ||||||
| /never married | 67 (25) | 36 (39) | 9 (45) | 94 (28) | 5 (31) | 98 (29) | |||
| Married/living with a partner | 196 (75) | 56 (61) | 11 (55) | 241 (72) | 11 (69) | 241 (71) | |||
| Substance use | |||||||||
| Current smoker | 18 (7) | 6 (6) | 0.92 | 2 (10) | 22 (7) | 0.63 | 21 (6) | 3 (19) | 0.08 |
| ≥ 15 drinks/month | 67 (24) | 8 (9) | 0.001 | 5 (24) | 70 (20) | 0.66 | 5 (29) | 70 (20) | 0.32 |
| Ever used illegal drugs | 163 (62) | 51 (56) | 0.28 | 15 (75) | 199 (60) | 0.18 | 12 (75) | 202 (60) | 0.30 |
| Regular marijuana use: | 0.09 | 0.73 | 0.63 | ||||||
| Yes, ≤ 2 times/week | 33 (20) | 6 (12) | 2 (13) | 37 (19) | 1 (8) | 38 (19) | |||
| Yes, >2 times/week | 33 (20) | 6 (12) | 4 (27) | 35 (18) | 3 (25) | 36 (18) |