Table 1. Number of children and samples tested, and estimated seropositivity cutoffs by country and antigen included in the seroepidemiologic analyses.

			Seropositivity cutoff, log10 IgG (MFI-bg) *
	N	N	External	Mixture	Presumed
	children	samples	Reference	Model	Unexposed
Leogane, Haiti
Giardia VSP-3	142	771	2.42	1.64	2.11
Giardia VSP-5	142	771	2.31	1.46	1.88
Cryptosporidium Cp17	142	771	2.26	2.00	2.58
Cryptosporidium Cp23	142	771	2.70	2.75	2.57
E. histolytica LecA	142	771	2.48	2.30	1.93
Salmonella LPS group B	142	771		1.60	1.37
Salmonella LPS group D	142	771		1.48	2.48
ETEC LT B subunit	142	771			2.86
Norovirus GI.4	142	771		2.51	2.09
Norovirus GII.4.NO	142	771		2.04	2.24
Asembo, Kenya
Giardia VSP-3	240	445	2.81	1.62	1.67
Giardia VSP-5	240	445	2.65	1.82	1.67
Cryptosporidium Cp17	240	445	2.63	2.58	2.38
Cryptosporidium Cp23	240	445	3.14	3.40	2.36
E. histolytica LecA	240	445		1.89
Salmonella LPS group B	240	445		1.36
Salmonella LPS group D	240	445		1.41
ETEC LT B subunit	240	445			2.79
Cholera toxin B subunit	240	445			2.91
Campylobacter p18	240	445			2.11
Campylobacter p39	240	445		2.61	2.57
Kongwa, Tanzania
Giardia VSP-3	4989	4989	2.23	2.04
Giardia VSP-5	4989	4989	2.15	2.27
Cryptosporidium Cp17	4989	4989	2.26
Cryptosporidium Cp23	4989	4989	2.58
E. histolytica LecA	4989	4989	1.97	2.50
Salmonella LPS group B†	902	902
Salmonella LPS group D†	902	902
ETEC LT B subunit	4989	4989
Cholera toxin B subunit‡	4087	4087
Campylobacter p18†	902	902
Campylobacter p39†	902	902

^*Seropositivity cutoffs determined using external reference samples (typically ROC curves except for Giardia and E. hystolitica in Haiti), finite Gaussian mixture models, or distribution among the presumed unexposed (see Materials and methods for details). External reference cutoffs vary across cohorts for the same antigen due to use of different bead sets in each cohort. External reference cutoffs reported from years (2013–2015) in Tanzania, estimated among 4087 samples. Cutoff values are missing if they could not be estimated in each method; cutoff values based on the presumed unexposed required longitudinal measurements within individual children and therefore could not be estimated for any antigen in the repeated cross-sectional design in Tanzania.

^† Measured only in year 1 of the study (2012).

^‡ Measured only in years 2–4 of the study (2013–2015).