Table 2.

Areas of Greater Increases and Decreases in Blood Flow with Stress Challenge in CAD Patients without Depression (N=15)

Increased Blood Flow						Decreased Blood Flow
Z Score*	Voxel Number*	Talairach Coordinates				Z Score*	Voxel Number**	Talairach Coordinates
		x	y	z	Brain Region			x	y	z	Brain Region
5.92	5026	−8	24	64	L. Sup Frontal Gyrus (6)	7.33	9775	52	−6	14	R Inf Frontal Gyrus (44)
5.12		−50	28	18	L. Middle/Inferior Frontal Gyrus (45,46)	7.31		58	−6	14
4.95		−48	20	34	L. Middle Frontal Gyrus (9)	6.99		62	−22	20	R. Postcentral Gyrus (43)
4.67	1199	−66	−42	−10	L. Middle Temporal Gyrus (21)	4.40	4449	−6	−6	44	Posterior Cingulate
4.26		−54	−40	−18	L. Inf. Temporal Gyrus (20)	4.35		2	−44	54	Precuneus (7)
3.79		−55	−52	2	L. Middle Temporal Gyrus (21)	4.34		8	−10	64	R. Sup Frontal Gyrus (6)
4.53	1343	−60	−52	40	L Parietal-Supramarginal Gyrus (40)	7.32	4730	−52	−10	22	L. Postcentral Gyrus (32)
4.51		−30	−66	50	L Parietal-Inf Parietal Lobule (40)	4.81		−34	0	4	L Sup Temp Gyrus (42)
3.77		−35	−50	34		4.67		−30	−26	12
3.74	132	72	−30	−12	R Middle Temporal Gyrus (20, 21)	3.90	408.00	22	−62	−26	cerebellum
3.39	68	58	10	−22	R. Sup Temp. Gyrus (38)	3.69		20	−55	−18
2.82		50	6	−34		3.66	466.00	−10	−66	−20	cerebellum
3.28		20	34	−12	R Sup Frontal Gyrus (11)	3.65		−24	−52	−28
4.32	288	52	28	−18	R Sup Temp Gyrus (38)	3.63	163.00	20	−32	−16	cerebellum
4.06		34	26	−30		3.13		24	−4	−44
3.82		44	26	v24		3.10		6	−14	−40
2.87		10	26	48	R Sup Frontal Gyrus (8)
4.11	283	24	54	−16	R Sup Frontal Gyrus (11)
3.74		24	48	−22	R Medial Orbital Gyrus (11,47)
3.28		20	34	−12	R Sup Frontal Gyrus (11)
3.46	127	16	28	54	R Sup Frontal Gyrus (8)
2.87		10	26	48
3.56	52	−30	−26	−10	L. Hippocampus
3.26	70	4	−28	−16	midbrain
4.15	683	8	−88	−34	cerebellum
3.55		38	−70	−44
3.26		40	−68	−36

^*Z Score>2.67, p<.005

^**Number of voxels within the activated cluster

Areas in bold represent the voxel with greatest activation in a contingent group of voxels; non-bold areas are other areas of activation within the same group