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. 2019 Sep 16;2019(9):CD012643. doi: 10.1002/14651858.CD012643.pub2
Methods Secondary citation(s)
  • NA


Language of publication
  • English


Study design
  • Retrospective, single‐centre study


Study centre(s)
  • University Hospital of Limoges, France


Country
  • France


Median follow‐up time (range)
  • 65.8 months (2.2‐194.5)

Participants Number of included participants
  • Total: 158

  • With interim‐PET: 68


Inclusion criteria
  • Histologically proven, classic HL


Exclusion criteria
  • Nodular lymphocyte predominant HL


Consent
  • Not reported


Recruitment period
  • February 1995 to July 2011


Age (range, in years)
  • 38 (16‐85)


Ethnic group(s)
  • Not reported


Stages of disease
  • All stages


Comorbidities
  • Not reported


Therapy regimen
  • According to the standard of care at the time of diagnosis therapy regimens included ABVD, MOPP/ABV hybrid or BEACOPP; number of cycles not reported

Prognostic factor(s) Prognostic factor(s)
  • Interim PET


Definition of prognostic factor(s)
  • Not reported


Timing of prognostic factor measurement
  • After cycle 2 of chemotherapy


Method for measurement (use of specific scale and cut‐off)
  • Visual evaluation

  • PET‐positive if focal or diffuse accumulation of FDG in lesions higher than in surrounding tissue

  • FDG‐PET‐CT data (2005 and later) retrospectively reinterpreted using the Deauville 5‐point scoring system


Was the same definition and method for measurement used in all participants?
  • Different PET imaging techniques over time (dual‐head coincidence until 2005, then FDG‐PET‐CT), quality assurance and quality control program to ensure comparability of methods


Were prognostic factor(s) assessed blinded for outcome(s), and for each other (if relevant)?
  • Not reported

Notes Conflict of interest
  • Not reported


Funding
  • This work was supported by the University Hospital of Limoges, CHU Limoges, F‐87042 France.