Table 1.
Baseline Characteristics.
| Prasugrel group (n=250) |
Clopidogrel group (n=250) |
p value | ||
|---|---|---|---|---|
| Age: yrs | 67.7±10.0 | 67.2±11.2 | 0.568 | |
| Male: n (%) | 50 (20.4) | 51 (20.4) | 0.911 | |
| Hypertension: n (%) | 186 (74.4) | 186 (74.4) | 1.000 | |
| Diabetes: n (%) | 106 (42.4) | 93 (37.2) | 0.235 | |
| Dyslipidemia: n (%) | 177 (70.8) | 159 (63.6) | 0.086 | |
| Smoking: n (%) | 140 (56.0) | 148 (59.2) | 0.469 | |
| Body weight<50 kg: n (%) | 25 (10.0) | 22 (8.8) | 0.646 | |
| eGFR: mL/min/1.73m2 | 73.5±23.1 | 73.5±23.1 | 0.428 | |
| Underlying disease: n (%) | 0.207 | |||
| Chronic CAD | 134 (53.6) | 148 (59.2) | ||
| ACS | 116 (46.4) | 102 (40.8) | ||
| Affected vessels: n (%) | 0.230 | |||
| Single vessel disease | 175 (70.0) | 187 (74.8) | ||
| Multi-vessel disease | 75 (30.0) | 63 (25.2) | ||
| Syntax score | 14.0±9.3 | 12.1±8.0 | 0.013 | |
| Approach: n (%) | 0.720 | |||
| Radial | 130 (52.0) | 134 (53.6) | ||
| Femoral | 120 (48.0) | 116 (46.4) | ||
| PCI for LAD: n (%) | 122 (48.8) | 139 (55.6) | 0.128 | |
| DES: n (%) | 199 (79.6) | 128 (51.2) | <0.0001 | |
| Anticoagulants: n (%) | ||||
| Warfarin | 9 (3.6) | 11 (4.4) | 0.648 | |
| DOAC | 9 (3.6) | 13 (5.2) | 0.383 | |
eGFR: estimated glomerular filtration rate, CAD: coronary artery disease, ACS: acute coronary syndrome, PCI: percutaneous coronary intervention, LAD: left anterior descending artery, DES: drug-eluting stent, DOAC: direct oral anticoagulant
*Multi-vessel disease includes two-vessel, three-vessel and left main coronary artery diseases