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. 2019 Sep 16;9:13304. doi: 10.1038/s41598-019-49453-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Retinal disease-associated gene expression. (A) UpSet diagram showing the number of genes in each disease set from DisGeNet. Genes that are distinct to each set are in the first four columns. Genes shared among sets are in the last three columns; (B) Log2 fold-change values of disease-associated genes. Genes are plotted from left to right in order of adjusted p-value. Bars are colored by the magnitude of the adjusted p-value. Adjusted p-values are further annotated based on their order of magnitude. The plot for retinitis pigmentosa displays the top 20 most significant genes based on adjusted p-value. All other diseases are displaying all of their associated genes.