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. 2019 Sep 16;9:13351. doi: 10.1038/s41598-019-49956-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene richness (i.e. the number of unique genes) for each sample per method and connected as sample pairs. Circle vs triangle shapes represent pre-HSCT vs post-HSCT samples respectively. Box plots show interquartile ranges (minimum and maximum values as whiskers) for gene richness per sampling method. A Wilcoxon paired test found no significant difference in the mean gene richness between fresh-frozen (FF) and stabilized-frozen (SF) samples. This figure has been created with help of the R(v3.5.0)²⁹/PhyloSeq³⁷ package.