Table 2.

Summary of investigated alterations in median fin fold gene expression in fndc3a^wue1/wue1 mutants at 20–22 hpf, at 48 hpf, after fndc3a Morpholino and FNDC3A RNA (rescue) injection at 20–22 hpf.

Gene	Alterations of gene expression in fndc3awue1/wue1
	20–22 hpf	48 hpf
fras1 hmcn1	loss in ventral mff region between the cloaca and the tail bud tip	reduced expression
hmcn2 bmp1a fbln1	loss of ventral mff structures posterior to proctodeum, convergence or even fusion of somites at ventral positions	similar to 20–24 hpf but slightly increased expression in cells of the posterior fin tip
and1	reduction in ventral mff region between the cloaca and the tail bud tip	recovered in fin folds compared to 20–22 hpf, but slightly weaker than wildtype
	+ fndc3a Morpholino	+ FNDC3A RNA (rescue)
fras1 hmcn1	complete loss of ventral mff expression	regained ventral mff expression after RNA rescue
hmcn2	complete loss of ventral mff structures, ventrally shifted expression domain	regain of mff structures, expression domain not ventrally shifted
bmp1a; fbln1; and1	not analyzed	not analyzed