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. 2019 Sep 16;9:13295. doi: 10.1038/s41598-019-49840-4

Table 1.

Profiles of patients from which mucosal biopsies were collected.

Pt # Symptoms Medication Pathology Endoscopy
1 none none normal tissue none
2 none none normal tissue none
3 none none normal tissue none
4 none none normal tissue none
5 flare-up, 15–20 bm/d Steroids, biologic chronic inflammation, severe activity pancolitis, Mayo 3 distal, 2 proximal
6 flare-up, 10 bm/d none chronic inflammation, moderate to severe activity pancolitis, Mayo 2
7 chronic active, 4 bm/d none chronic inflammation, mild activity proctitis, Mayo 1
8 chronic active, 2–3 bm/d 5-ASA chronic inflammation, marked activity pancolitis, Mayo 3 distal, 2 proximal
9 new onset, 6–8 bm/d none chronic inflammation, moderate activity pancolitis, Mayo 2
10 chronic active, 12 bm/d* Steroid enema, 5-ASA chronic inflammation, mild activity proctitis, Mayo 2
11 flare-up, 6–8 bm/d Imuran acute, chronic inflammation, deep ulcers ileocolitis, deep ulcers
12 flare-up, 4–5 bm/d 5-ASA chronic inflammation, severe activity colitis
13 flare-up, pain, +2 bm/d 5-ASA normal tissue; chronic stricture with no active inflammation ileal stricture, blind biopsies
14 flare-up, 2–5 bm/day none chronic inflammation, moderate activity pancolitis, Mayo 1–2

5-ASA = 5 aminosalicylic acid; *mucous, but infrequent stool; **suspected flare up initially but with further imaging dx. with chronic stricture with no active inflammation; bm = bowel movement, most were bloody.