Table 1.
The relationship between the expressions of Rab1A and mTOR relevant gene targets including HER2, EGFR, AKT, S6K, GLI1 and mTOR in TCGA database.
| Rab1A | No. of | |||||||
|---|---|---|---|---|---|---|---|---|
| ESCA | STAD | COAD | READ | LIHC | CHOL | PAAD | P < 0.05 | |
| mTOR | 0.022 | <0.001 | <0.001 | <0.001 | <0.001 | 0.004 | <0.001 | 7 |
| S6K | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | 0.018 | <0.001 | 7 |
| GLI1 | 0.751 | 0.986 | 0.172 | 0.172 | <0.001 | 0.573 | <0.001 | 2 |
| AKT | 0.024 | <0.001 | <0.001 | <0.001 | <0.001 | 0.001 | <0.001 | 7 |
| HER2 | 0.847 | 0.029 | 0.284 | 0.284 | 0.001 | 0.550 | 0.211 | 2 |
| EGFR | 0.120 | 0.015 | 0.009 | <0.001 | <0.001 | 0.026 | <0.001 | 6 |
Abbreviations: ACC: adrenocortical carcinoma. BLCA: bladder urothelial carcinoma. BRCA: breast invasive carcinoma. CESC: cervical squamous cell carcinoma and endocervical adenocarcinoma. CHOL: cholangio carcinoma. COAD: colon adenocarcinoma. DLBC: lymphoid neoplasm diffused large B-cell lymphoma. ESCA: esophageal carcinoma. GBM: glioblastoma multiforme. HNSC: head and neck squamous cell carcinoma. KICH: kidney chromophobe. KIRC: kidney renal clear cell carcinoma. KIRP: kidney renal papillary cell carcinoma. LAML: acute myeloid leukemia. LGG: brain lower grade glioma. LIHC: liver hepatocellular carcinoma. LUAD: lung adenocarcinoma. LUSC: lung squamous cell carcinoma. OV: ovarian serous cystadenocarcinoma. PAAD: pancreatic adenocarcinoma. PCPG: pheochromocytoma and paraganglioma. PRAD: prostate adenocarcinoma. READ: rectum adenocarcinoma. SARC: sarcoma. SKCM: skin cutaneous melanoma. STAD: stomach adenocarcinoma. TGCT: testicular germ cell tumors. THCA: thyroid carcinoma. THYM: thymoma. UCEC: uterine corpus endometrial carcinoma. UCS: uterine carcinosarcoma.