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. 2019 Sep 16;9:13307. doi: 10.1038/s41598-019-49791-w

Table 1.

Summary of the recorded data.

w (ms) Δ (ms) No. of cells V50/V50n1 E50/E50n1
n = 2 n = 3 n = 2 n = 3
mean ± SD mean ± SD mean ± SD mean ± SD
1 0.5 8 0.71 ± 0.07# 0.64 ± 0.07 # 1.01 ± 0.20 ND 1.24 ± 0.27*
1 8 0.74 ± 0.05# 0.66 ± 0.07 # 1.10 ± 0.14 ND 1.30 ± 0.28*
2 1 7 0.79 ± 0.05# 0.72 ± 0.02 # 1.24 ± 0.15** 1.56 ± 0.10#
2 7 0.82 ± 0.06# 0.72 ± 0.06 # 1.36 ± 0.18** 1.58 ± 0.24#
5 1 9 0.83 ± 0.07# 0.75 ± 0.07 # 1.38 ± 0.23# 1.71 ± 0.31#
5 12/6 0.89 ± 0.06# 0.85 ± 0.08 ** 1.59 ± 0.20# 2.20 ± 0.39#

Mean values ± standard deviation are presented for normalized threshold voltage (V50/V50n1) and energy expenditure (E50/E50n1) from the stimulation sequences with multiple pulses (n = 2 or 3), relative to single pulse (n = 1). Measurements were made at fixed pulse width w and interval Δ between the pulses. Comparison with n = 1 pulses was done with one-sample t-test against value 1. Effect size shown as follows: ND - no difference; *p < 0.05; **p < 0.01; #p < 0.001. Note that in the case w = 5 and Δ = 5 the number of cells used in statistics was 12 and 6 for n = 2 and 3, respectively.