Table 1.
IgE-autoantigens (“autoallergens”) described in atopic dermatitis.
| IgE against | Prevalence | References |
|---|---|---|
| Manganese superoxide dismutase (MnSOD, SOD2) | 42% | (8, 17) |
| Ribosomal protein P2 (RPLP2) | 8% | (18) |
| Profilin 1 (PFN1) | n.a. | (19) |
| Thioredoxin (TXN, hTrx) | n.a. | (20) |
| SART-1/Hom s1 | n.a. | (19) |
| α-NAC/Hom s2 | 30% | [(21); own observations] |
| BCL7B/Hom s3 | n.a. | (21) |
| MICU1/Hom s4 | 16.7% | (12, 21) |
| Cytokeratin 6A/Hom s5 | n.a. | (21) |
| Cyclophilins A, B, C (PPIA, PPIB, PPIC) | n.a. | (22) |
| Dense fine spreckles (DFS70/LEDGF) | 10–30% | (23, 24) |
| Actin-α | 15.5% | (11) |
| Tubulin-α | 21.7% | (11) |
| eIF6 | 25.4% | (11) |
| HLA-DR-α | 8.7% | (11) |
| RP-1 | 21% | (11) |
| >124 further antigens | n.a. | (11) |