Table 2.
Frequently found MHC-presented epitopes of exemplary autoallergens.
| Autoallergen | MHC class | Consensus sequence of overlapping epitopes | # of epitopes found | # of studies | HLA |
|---|---|---|---|---|---|
| DSF70 | I | ATASVNLKVSPK | 62 | 8 | A*03:01 A*68:01 A*11:01 A*31:01 |
| KVSQVIMEKSTMLY | 61 | 8 | A*01:01 A*03:01 A*68:01 |
||
| KAVDITTPKAA | 12 | 4 | A*03:01 A*11:01 |
||
| SVITQVLNK | 10 | 4 | A*03:01 A*68:01 A*11:01 A*30:01 |
||
| α-NAC/Hom s2 | I | ANVSRAKAVRAL | 40 | 8 | B*07:02 C*06:02 B*39:24 |
| QENTQTPTV | 5 | 4 | B*40:01 B*40:02 B*45:01 |
||
| KSKNILFVITK | 4 | 1 | A*11:01 B*57:01 |
||
| II | NVSRAKAVRALKNNSNDIVNA | 9 | 1 | n.a. | |
| EEVDETGVEVKD | 3 | 1 | n.a. | ||
| LSQQAQLAAAEKF | 2 | 1 | n.a. | ||
| BCL7B/Hom s3 | I | EEDSGAPPLKRF | 9 | 6 | B*44:02 B*44:03 |
| KVMAAIEKVRK | 2 | 2 | A*03:01 | ||
| MICU1/Hom s4 | I | RPTTGNTL | 24 | 7 | B*07:02 |
| VTASTGLLWK | 7 | 5 | A*03:01 A*11:01 |
||
| AELAVGSRW | 12 | 6 | B*44:02 B*44:03 |
||
| II | RSITPNEKQPEHLGLDQY | 5 | 1 | n.a. |
This list was extracted from the SysteMHCAtlas (66). This list is not exhaustive.