. 2019 Sep 10;13:411. doi: 10.3389/fncel.2019.00411

TABLE 1.

Prion agent strains analyzed in this study.

Strain	Disease	Origin	Passage	Passage/line	References
ME7	Natural sheep scrapie	Suffolk sheep	9^th	C57Bl/Dk	Zlotnik and Rennie, 1963
22A	Experimental sheep scrapie SSBP1	Cheviot sheep	10^th	VM/Dk	Dickinson and Meikle, 1969
22C	Experimental sheep scrapie SSBP1	Cheviot Sheep	8^th	C57Bl/Dk	Dickinson, 1976
22F	Experimental sheep scrapie SSBP1	Cheviot Sheep	9^th	C57Bl/Dk	Dickinson, 1976
22L	Experimental sheep scrapie SSBP1	Cheviot Sheep	13^th	C57Bl/Dk	Dickinson, 1976
79A	Experimental sheep scrapie SSBP1	‘Drowsy’ goat	12^th	C57Bl/Dk	Dickinson, 1976; Pattison and Millson, 1961
79V	Experimental sheep scrapie SSBP1	‘Drowsy’ goat	5^th	VM/Dk	Dickinson, 1976; Pattison and Millson, 1961
80A	Experimental sheep scrapie SSBP1	‘Scratching’ goat	5^th	C57Bl/Dk	Pattison and Millson, 1961
87A	Natural sheep scrapie	Cheviot × Border Leicester sheep	9^th	C57Bl/Dk	Bruce et al., 1976
87V	Natural sheep scrapie	Cheviot x Border Leicester sheep	9^th	VM/Dk	Bruce et al., 1976
139A	Experimental sheep scrapie SSBP1	‘Drowsy’ goat Chandler isolate	9^th	C57Bl/Dk	Chandler, 1961; Pattison and Millson, 1961
221C	Natural sheep scrapie	Halfbreed sheep	4^th	C57Bl/Dk	Bruce et al., 2002
301C	BSE	Holstein-Fresian cow	7^th	C57Bl/Dk	Bruce et al., 1994
301V	BSE	Holstein-Fresian cow	7^th	VM/Dk	Bruce et al., 1994
409V	CWD	Mule deer	5^th	VM/Dk	Bruce et al., 2002^∗

^∗Confirmed US CWD case material identified circa 1980 provided by Stuart Young and Beth Williams, Wild Animal Disease Center and Department of Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States (Williams and Young, 1980).