TABLE 1.
Low dose |
High dose |
|||
Log10CFU |
Log10CFU |
|||
d30 | d60 | d30 | d60 | |
M. africanum (L6) | 2.62 ± 0.022 | 2.45 ± 0.021 | 3.012 ± 0.129 | 2.89 ± 0.068 |
Mtb HN878 (L2) | 6.078 ± 0.087 | 5.723 ± 0.110 | 7.453 ± 0.138 | – |
Mtb H37Rv (L4) | 4.866 ± 0.0898 | 5.024 ± 0.296 | – | 5.203 ± 0.314 |
C57BL/6 mice were infected via aerosol with a low (<200 CFU) or high dose (>500 CFU) of the indicated bacteria and on day 30 or 60 post-infection the lungs were collected and the bacterial burden determined by CFU enumeration. Data are shown as mean ± SEM from at least five animals per time point. Mtb, M. tuberculosis; L, lineage.