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. 2019 Sep 10;10:992. doi: 10.3389/fphar.2019.00992

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Copyright © 2019 Liu, Zhang, Huang, Wang, Zheng, Lu, Zeng, Chen and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of HDD on adenine-induced CKD. (A) Body weight. (B) Serum albumin. (C) Blood urea nitrogen. (D) Serum creatinine. (E) PAS staining. (F) Masson staining. Data are presented as the means ± SEM, n = 6 rats per group (**P < 0.01, ***P < 0.001 compared with the control group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 compared with the CKD group).