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. 2019 Sep 10;10:992. doi: 10.3389/fphar.2019.00992

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Copyright © 2019 Liu, Zhang, Huang, Wang, Zheng, Lu, Zeng, Chen and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The score plots from PCA and OPLS-DA model. (A) PCA-X score plot of positive ion mode. (B) OPLS-DA score plot of positive ion mode. (C) PCA-X score plot of negative ion mode. (D) OPLS-DA score plot of negative ion mode. ESI⁺ means the positive electrospray ionization. ESI⁻ means the negative electrospray ionization. Green circle corresponds to the control group; blue circle corresponds to the CKD group.