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. 2019 Sep 10;10:961. doi: 10.3389/fphar.2019.00961

Figure 2.

Figure 2

In vitro antiviral effects of DPEP, LEP and LMEP against influenza A virus by different ways of drug delivery. MDCK cells (5×104 cells/well) were treated with varying concentrations of DPEP (A) and LEP (B), LMEP (C) with the ways of pre-treatment host cells prior to virus infection, limited treatment to 1 hour during virus infection, pre-treatment of virus with drug or post-treatment host cells after virus infection. **P < 0.01 compared with the way of pre-treatment host cells prior to virus infection, *P < 0.05 compared with the way of pre-treatment host cells prior to virus infection; △△ P < 0.01 compared with the way of limited treatment to 1 hour during virus infection, P < 0.05 compared with the way of limited treatment to 1 hour during virus infection; ▲▲ P < 0.01 compared with the way of pre-treatment of virus with drug, P < 0.05 compared with the way of pre-treatment of virus with drug. (D) ER (%) of DPEP, LEP and LMEP against influenza A virus in the way of post-treatment host cells after virus infection. **P< 0.01 compared with LMEP, *P < 0.05 compared with LMEP; △△ P < 0.01 compared with LEP, P < 0.05 compared with LEP.