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. 2019 Sep 10;10:961. doi: 10.3389/fphar.2019.00961

Table 2.

The inhibitory effect of LEP and DPEP on lung index of infected mice (n = 6).

Groups Dose
(mg/kg)
Day 3 Day 7
Lung insdex (x¯±s) Inhibition ratio of lung index (%) Lung index
x¯±s
Inhibition ratio of lung index (%)
Control uninfected / 0.67 ± 0.05 / 0.64 ± 0.04 /
Control infected / 1.26 ± 0.16△△ / 1.93 ± 0.14△△ /
Oseltamivir 22 0.74 ± 0.03** 41.27 1.18 ± 0.11** 38.86
LEP-treated 40 0.90 ± 0.05** 28.57 1.45 ± 0.16** 24.87
20 0.82 ± 0.11** 34.92 1.37 ± 0.06** 29.02
10 0.97 ± 0.09** 23.02 1.57 ± 0.10** 18.65
DPEP-treated 40 0.89 ± 0.06** 29.37 1.44 ± 0.11** 25.39
20 0.75 ± 0.13** 40.48 1.39 ± 0.08** 28.00
10 0.95 ± 0.08** 24.60 1.60 ± 0.23* 17.10

△△P < 0.01 compared with the control uninfected group; **P < 0.01 compared with the control infected group, *P < 0.05 compared with the control infected group.