Table 2.
Groups | Dose (mg/kg) |
Day 3 | Day 7 | ||
---|---|---|---|---|---|
Lung insdex | Inhibition ratio of lung index (%) | Lung index |
Inhibition ratio of lung index (%) | ||
Control uninfected | / | 0.67 ± 0.05 | / | 0.64 ± 0.04 | / |
Control infected | / | 1.26 ± 0.16△△ | / | 1.93 ± 0.14△△ | / |
Oseltamivir | 22 | 0.74 ± 0.03** | 41.27 | 1.18 ± 0.11** | 38.86 |
LEP-treated | 40 | 0.90 ± 0.05** | 28.57 | 1.45 ± 0.16** | 24.87 |
20 | 0.82 ± 0.11** | 34.92 | 1.37 ± 0.06** | 29.02 | |
10 | 0.97 ± 0.09** | 23.02 | 1.57 ± 0.10** | 18.65 | |
DPEP-treated | 40 | 0.89 ± 0.06** | 29.37 | 1.44 ± 0.11** | 25.39 |
20 | 0.75 ± 0.13** | 40.48 | 1.39 ± 0.08** | 28.00 | |
10 | 0.95 ± 0.08** | 24.60 | 1.60 ± 0.23* | 17.10 |
△△P < 0.01 compared with the control uninfected group; **P < 0.01 compared with the control infected group, *P < 0.05 compared with the control infected group.