TABLE 1.
Genes and gene versions enriched in 123 clinical isolates, sorted by significance.
| Gene name | SH_ref | Annotation | Clinical (%) | Commensal (%) |
| NA | SH1612 | Acetyltransferase GNAT | 86.2 | 4.4 |
| aacA-aphD | SH1611 | Bifunctional AAC/APH | 85.4 | 4.4 |
| folPX | SH2496 | Dihydropteroate synthase | 78.9 | 0.0 |
| folBX | SH2495 | Dihydroneopterin aldolase | 78.1 | 0.0 |
| NA | SH2607 | AtP-binding protein (plasmid) | 76.4 | 2.2 |
| paaZ | SH0090 | Bifunctional protein PaaZ | 85.4 | 13.0 |
| mecA | SH0091 | Methicillin resistance gene | 85.4 | 13.0 |
| ugpQ | SH0089 | Glycerophosphodiester phosphodiesterase | 82.1 | 13.0 |
| blaR1X | SH1763 | Regulatory protein BlaR1 | 84.6 | 19.6 |
| tagE | SH2252 | Truncated glycosyltransferase | 86.2 | 21.7 |
| blaZX | SH1764 | Beta-lactamase | 78.1 | 15.2 |
| blaIX | SH1762 | Penicillinase repressor | 60.2 | 2.2 |
| ansAX | SH1433 | Putative L-asparaginase | 55.3 | 0.0 |
| NAX | SH2156 | Ferrichrome ABC transporter truncated | 88.6 | 30.4 |
| nikAX | SH0292 | Nickel-binding periplasmic protein | 94.3 | 41.3 |
| fabGX | SH0438 | FabG | 89.4 | 32.6 |
| NA | SH0155 | MFS transporter | 96.8 | 47.8 |
| sraPX | SH0326 | SraP | 96.8 | 47.8 |
| secA2X | SH0331 | Protein translocase subunit SecA2 | 96.8 | 47.8 |
| yjjGX | SH0452 | Pyrimidine 5’-nucleotidase YjjG | 84.6 | 26.1 |
| PHAGE | StauST398-2/vB_saus_phi2 | 51.2 | 0.0 |
All these genes/gene versions were significantly enriched in clinical isolates (p < 0.001), the order of presentation from top of the table indicates those with the lowest p values. X These genes exist in different conserved versions in the clinical and commensal isolates. SH_ref; S. haemolyticus reference gene numbers from Takeuchi et al. (2005), accession number AP006716.1. The complete list of genes can be found in Supplementary Data S2.