TABLE 4.
Genes and gene versions enriched in 46 commensal isolates, sorted by significance.
| Gene name | SH_ref | Annotation | Clinical (%) | Commensal (%) |
| folBX | SH2495 | Dihydroneopterin aldolase | 22.0 | 100.0 |
| folPX | SH2496 | Dihydropteroate synthase | 23.6 | 100.0 |
| group_2286 | Major Facilitator (MFS) | 0.0 | 56.5 | |
| csoR | Copper-sensing transcriptional repressor CsoR | 8.1 | 76.1 | |
| copZ | Copper chaperone CopZ | 8.1 | 73.9 | |
| copA | Copper-exporting P-type ATPase | 8.1 | 71.7 | |
| czcD | Cadmium, cobalt and zinc/H(+)-K(+) antiporter | 8.1 | 71.7 | |
| NAX | SH0287 | Caax amino terminal protease family protein | 4.1 | 63.0 |
| arsR | ArsR family transcpriptional regulator | 4.1 | 63.0 | |
| ISSha1X | SH2073 | Transposase | 0.0 | 47.8 |
| grxC | Glutaredoxin | 8.1 | 69.6 | |
| nikAX | SH0292 | Nickel-binding periplasmic protein | 4.1 | 60.9 |
| ydaFX | SH2658 | Putative ribosomal N-acetyltransferase YdaF | 7.3 | 65.2 |
| recQ | SH1430 | ATP-dependent DNA helicase RecQ | 44.7 | 100.0 |
| ansAX | SH1433 | Putative L-asparaginase | 45.5 | 100.0 |
| IS30 | IS30 family transposase | 1.6 | 47.8 | |
| yjaB | Putative N-acetyltransferase YjaB | 2.4 | 50.0 | |
| group_1785 | Putative Insertion element/transposase | 2.4 | 50.0 | |
| IS1272X | SH2041 | IS1272 | 0.0 | 39.1 |
| yodJ X | SH0186 | Putative carboxypeptidase YodJ | 2.4 | 47.8 |
All these genes/gene versions were significantly enriched in commensal isolates (p < 0.001), the order of presentation from top of the table indicates those with the lowest p values. X These genes exist in different conserved versions in the clinical and commensal isolates. SH_ref; S. haemolyticus reference gene numbers from Takeuchi et al. (2005), accession number AP006716.1. The complete list of genes can be found in Supplementary Data S2.