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. 2019 Aug 24;20(17):4139. doi: 10.3390/ijms20174139
3-D 3-dimensional
C6S chondroitin-6-sulfate
ECM extracellular matrix
ERT enzyme replacement therapy
GAG glycosaminoglycans
GALNS N-acetylgalactosamine 6-sulfate sulfatase
HS heparan sulfate
HSCT hematopoietic stem cell transplantation
IS internal standard
KS keratan sulfate
LC-MS/MS liquid chromatography/tandem mass spectrometry
MPS Mucopolysaccharidosis
PBS phosphate buffered saline
SDET substrate degradation enzyme therapy
TLR4 toll-like receptor 4