Table 1.
Final body weight, final body weight gain, pH and β-glucuronidase (β-GA) in the caecum, colon, and feces content at week 16 of the treatment.
| Groups | Final Body Weight (g) | Final Body Weight Gain (g) | Caecum | Colon | Feces | |||
|---|---|---|---|---|---|---|---|---|
| pH | β-GA 1 | pH | β-GA 1 | pH | β-GA 1 | |||
| Normal | 39.56 ± 1.01 a | 8.41 ± 0.95 b | 7.12 ± 0.04 b | 3.22 ± 0.33 c | 7.21 ± 0.07 ab | 2.61 ± 0.16 bc | 6.99 ± 0.10 b | 5.72 ± 0.03 de |
| AOM + DSS control | 40.46 ± 1.01 a | 9.85 ± 0.68 b | 7.47 ± 0.04 a | 6.56 ± 0.35 a | 7.42 ± 0.03 a | 5.34 ± 0.53 a | 8.08 ± 0.13 a | 9.52 ± 0.08 a |
| BF + AOM + DSS | 41.76 ± 1.29 a | 12.05 ± 1.03 a | 7.20 ± 0.14 ab | 3.32 ± 0.34 bc | 7.20 ± 0.06 ab | 1.85 ± 0.15 bc | 6.96 ± 0.10 b | 4.88 ± 0.14 ef |
| BF + LYC 20 + AOM + DSS | 41.71 ± 0.97 a | 11.71 ± 0.65 ab | 7.24 ± 0.04 ab | 2.68 ± 0.25 c | 7.20 ± 0.06 ab | 1.66 ± 0.09 c | 7.07 ± 0.20 b | 6.71 ± 0.26 c |
| BF + LYC 50 + AOM + DSS | 41.42 ± 0.97 a | 11.61 ± 0.71 ab | 7.17 ± 0.06 ab | 2.37 ± 0.24 c | 7.19 ± 0.07 b | 2.44 ± 0.27 bc | 7.04 ± 0.11 b | 4.71 ± 0.12 f |
| LYC 20 + AOM + DSS | 39.78 ± 0.70 a | 10.01 ± 0.44 ab | 7.39 ± 0.09 ab | 3.65 ± 0.24 bc | 7.36 ± 0.09 ab | 2.73 ± 0.21 bc | 7.19 ± 0.13 b | 6.26 ± 0.27 cd |
| LYC 50 + AOM + DSS | 41.19 ± 1.29 a | 12.10 ± 1.08 a | 7.29 ± 0.09 ab | 4.74 ± 0.22 b | 7.18 ± 0.07 b | 3.01 ± 0.31 b | 7.18 ± 0.16 b | 6.20 ± 0.10 cd |
| Metformin + AOM + DSS | 39.03 ± 1.01 a | 9.74 ± 1.14 b | 7.27 ± 0.11 ab | 2.99 ± 0.31 c | 7.28 ± 0.04 ab | 2.46 ± 0.27 bc | 7.02 ± 0.25 b | 7.62 ± 0.33 b |
Values are mean ± SEM (n = 6–10 animals per group). 1 μg phenolphthalein per hour per g of content. Values with different letter(s) within a column are significantly different (Tukey HSD α < 0.05). AOM: azoxymethane; DSS: dextran sulfate sodium; BF: Bifidobacterium longum; LYC: lycopene.