Figure 3.

Time course of change in SO₂ (A) and sPAP (B) in controls and HAPE-susceptibles (HAPE-S) during normobaric hypoxia (0–2 h) and at the Capanna Margherita (4559 m). Data on short-term normobaric hypoxia are from 15 controls and 17 HAPE-S from the study reported in [17], those from exposure to high-altitude (4559 m) are from 10 controls and 9 HAPE-S from reference [2]. In both studies, systolic pulmonary arterial pressure (sPAP) has been measured by Doppler echo-cardiography. Oxygen saturation (SO₂) was measured by pulse-oximetry. Mean values ± standard deviation; N: normoxia; * indicates difference between controls and HAPE.