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. 2019 Aug 22;20(17):4092. doi: 10.3390/ijms20174092

Figure 1.

Figure 1

Proposed mechanisms of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) modulation of alpha cell glucagon secretion in humans. AC: adenylate cyclase, ATP: adenosine triphosphate, cAMP: cyclic adenosine monophosphate, PKA: protein kinase A, GIPR: GIP receptor, GLP-1R: GLP-1 receptor, SSTR: somatostatin receptor.