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Nobiletin (NOB) improves cholesterol homeostasis in aged mice. (A) Serum total cholesterol levels, HDL cholesterol levels, LDL/VLDL cholesterol levels, and (B) LDL/HDL ratios were measured by colorimetric assays (n = 6–8). RD: regular diet; HF: high-fat diet; HF.NOB: high-fat diet with 0.1% NOB. *p < 0.05, **p < 0.01, ***p < 0.001, One-Way ANOVA; #p < 0.05, t-test. Bar graphs represent Mean ± SEM.
