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Nobiletin (NOB) enhances fecal bile acid excretion. Fecal taurine (A) and glycine (B) conjugated primary bile acid levels were measured in metabolomics (n = 10–12). RD: regular diet; HF: high-fat diet; HF.NOB: high-fat diet with 0.1% NOB. *p < 0.05, *** p < 0.001, One-Way ANOVA; #p < 0.05, t-test. For the box and whisker plots, box edges correspond to 25th and 75th percentiles, lines inside of the box correspond to 50th percentiles and whiskers include extreme data points.
