MDPI |
Multidisciplinary Digital Publishing Institute |
CRLM |
Colorectal liver metastasis |
HCC |
Hepatocellular carcinoma |
TME |
Tumor microenvironment |
GI |
Gastrointestinal |
NK cell |
Natural killer cell |
NKT cell |
Natural killer T cell |
MAIT cell |
Mucosal-associated invariant T cell |
Treg |
Regulatory T cell |
MDSC |
Myeloid-derived suppressor cell |
CD |
Cluster of differentiation |
IFN
|
Interferon gamma |
TNF
|
Tumor necrosis factor alpha |
TGF-
|
Tumor growth factor beta |
IL |
Interleukin |
NKG2 |
Natural killer group 2 receptor |
OxPhos |
Oxidative phosphorylation |
PPP |
Pentose-phosphate pathway |
mTOR |
Mammalian target of Rapamycin |
ATP |
Adenosine triphosphate |
cAMP |
Cyclic adenosine monophosphate |
LADH |
Lactate dehydrogenase |
IDO |
Indoleamine 2,3-dioxygenase |
TDO |
Tryptophan 2,3-dioxygenase |
NAD |
Nicotinamide adenine dinucleotide |
MCT |
Monocarboxylase transporter |
ADCC |
Antibody-dependent cell cytotoxicity |
PGE2 |
Prostaglandin E2 |
CA |
Carbonic anhydrase |
ROS |
Reactive oxygen species |
FAS |
Fatty acid synthase |
REDD1 |
Regulation of DNA damage response 1 |
HIF-1 |
Hypoxia inducible factor 1 |
MICA |
MHC class I polypeptide-related sequence A |
TRAIL |
TNF-related apoptosis-inducing ligand |
6PGDH |
6-Phosphogluconate dehydrogenase |
PI3K |
Phosphoinositide 3-kinase |
PKB |
Protein kinase B |
PDPK1 |
3-phosphoinositide-dependent protein kinase-1 |