Table 2.
Adjusted 1 percent change in seropositive anti-measles, anti-mumps, and anti-rubella levels in relation to child blood lead concentration.
| Anti−Measles | Anti−Mumps | Anti−Rubella | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood Lead Measure | N | % Diff 2 | 95% CI 3 | p Value | N | % Diff | 95% CI | p Value | N | % Diff | 95% CI | p Value |
| Categorical | ||||||||||||
| <1 µg/dL | 2634 | Ref | - | - | 2519 | Ref | - | - | 2581 | Ref | - | - |
| 1<5 µg/dL | 4570 | −5.49 | (−10.26, −0.46) | 0.034 | 4332 | −1.37 | (−4.80, 2.19) | 0.437 | 4510 | −2.90 | (−7.16, 1.56) | 0.194 |
| ≥5 µg/dL | 163 | −17.42 | (−30.62, −1.71) | 0.032 | 154 | −6.40 | (−19.99, 2.19) | 0.400 | 164 | 0.76 | (−25.75, 36.74) | 0.961 |
| Linear (per 1 µg/dL) 4 | 6832 | −2.18 | (−4.22, −0.09) | 0.041 | 6492 | −0.46 | (−1.30, 0.38) | 0.273 | 6719 | 0.42 | (−2.19, 3.10) | 0.751 |
| Linear (per 1 µg/dL) 5 | 6819 | −2.39 | (−4.66, −0.08) | 0.043 | 6480 | −0.40 | (−2.07, 1.31) | 0.638 | 6707 | 0.71 | (−2.27, 3.78) | 0.638 |
| Linear (per 1 loge) 6 | 6832 | −5.51 | (−9.90, −0.90) | 0.021 | 6492 | −1.42 | (−3.70, 0.91) | 0.224 | 6719 | 1.00 | (−3.86, 6.11) | 0.686 |
1 Adjusted for child sex, age (months), race/ethnicity (5 categories), family poverty to income ratio, NHANES cycle (1999–2000, 2001–2002, 2003–2004); 2 Percent difference in antibody level for each increment of exposure; 3 95% confidence interval; 4 Linear regression model with blood lead modelled as a continuous, untransformed concentration; 5 Linear regression model with blood lead modelled as a continuous, untransformed concentration, excluding blood lead concentrations ≥10 µg/dL; 6 Linear regression model with blood lead modelled as a continuous concentration, with loge tranformation.