Figure 2.

Venn diagram showing comparison of the number of identified proteins (A) in the current TMT based study and a previously published study; (B) in cytosolic and plasma membrane (PM) proteome. PLSDA scores plot showing clear separation of control and MSP1 treated proteins of (C) cytosolic and (D) PM proteome in component 1. Hierarchical clustering analysis of the differential proteins of cytosolic (E) and PM (F) fractions showing clear separation of up- and down-regulated proteins in response to MSP1 treatment. (G) Venn diagram showing distribution of differential proteins in the cytosolic and PM proteome after MSP1 treatment. (H) Functional annotation of the identified cytosolic, PM and commonly identified proteins, corresponding to Figure 2B using PANTHER protein class.