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Summary of advantages and disadvantages of distinct stem cell types.
| Stem Cells | Advantages | Disadvantages |
|---|---|---|
| ESCs | Unlimited self-renewal; Pluripotent [161] | Ethical issues; Uncontrolled differentiation [162,163] |
| NSCs | Multipotent [168] | Poor survival [169,170] |
| iPSCs | Autologous transplantation; Pluripotent [180] | Possible pathological phenotype [181,182] |
| MSCs | Easy handling; Multipotent; Intravenous application [190,192,193] | Low rate of neuronal differentiation [191] |
