Cell body area of Iba-1 + cells in the outer plexiform layer (OPL), inner plexiform layer (IPL), and nerve fiber—ganglion cell layer (NFL-GCL) in eyes untreated and treated with saffron extract at day 3 after ocular hypertension (OHT) induction. Histograms show the mean cell body area (± standard deviation, SD) of Iba-1 + cells. Abbreviations: Naïve age-matched control (NG), lasered group contralateral (LG3d contralateral), lasered group ocular hypertension (LG3d OHT), lasered group contralateral + saffron (SLG3d contralateral), lasered group ocular hypertension + saffron (SLG3d OHT). Statistical significance indicators: ** p < 0.01; vs. NG. +
p < 0.05, ++
p < 0.01 vs. LG3d OHT. ^^
p < 0.01; vs. LG3d contralateral.