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. 2019 Aug 28;20(17):4213. doi: 10.3390/ijms20174213

Figure 2.

Figure 2

Depiction of localization patterns of characterized Arabidopsis kinesin-12 throughout mitosis and cytokinesis. (A) POK1/Kin12C and POK2/Kin12D (orange) colocalize with microtubules (grey) of the preprophase band (PPB) in prophase. (B,C) Following PPB disassembly at the end of prophase, POKs are tethered to the plasma membrane occupying a region at the cell cortex that delineates the future division plane (cortical division zone, CDZ; orange) throughout the metaphase and anaphase. (D) During cytokinesis, PAKRP1/Kin12A, PAKRP1L/Kin12B, and POK2/Kin12D decorate the phragmoplast midzone (blue), contributing to the stabilizing of the interdigitated microtubules there. At the end of cytokinesis, phragmoplast peripheral microtubule plus-ends extend towards the lateral walls. POK1/Kin12C and POK2/Kin12D residing there mediate the guidance of the phragmoplast and the accurate cell plate (brown) navigation to the preselected cell plate fusion site (CPFS, orange). Image (A) shows a 3D-representation of the cell, while (B–D) depict median cell planes.