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. 2019 Aug 22;20(17):4095. doi: 10.3390/ijms20174095

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The chemical structure of MK-8776 (A), and the cell viability curve of human epidermoid carcinoma cell line KB-3-1 and its drug resistant KB-C2 cells (B), colon cancer cell line SW620 and doxorubicin-resistant SW620/Ad300 cells (C) that overexpress P-gp, HEK293/pcDNA3.1 and ABCB1 transfected HEK293/ABCB1 cells (D) upon treatment with MK-8776.