Skip to main content
. Author manuscript; available in PMC: 2019 Sep 17.
Published in final edited form as: J Pathol. 2019 Feb 20;247(5):574–588. doi: 10.1002/path.5229

Table 5.

The IARC variant classification scheme (Modified from Plon et al. 2008 [92]).

Category Synonym Definition

Pathogenic Post_P> 0.99
Likely Pathogenic 0.99 ≥ Post_P> 0.95
VUS Unclassified variant (UV) 0.95 ≥ Post_P ≥ 0.05
Likely Not Pathogenic Likely Benign 0.05 >Post_P ≥0.001
Not Pathogenic Benign Post_P< 0.001