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Sensitivity of CorA mutants in the presence of HexaCo
|
M. tuberculosis strain with (+) and without (–) 100 μM HexaCo |
CARA MBC (μM) of: |
|||
|---|---|---|---|---|
| Rif | 2504 | 2178 | HexaCoa | |
| WT– | 0.31 | 3.1 | 3.1 | >1,000 |
| WT+ | 0.31 | 3.1 | 3.1 | NA |
| 3(E212D)– | 0.31 | 12.5 | 12.5 | >1,000 |
| 3(E212D)+ | 0.31 | 3.1 | 3.1 | NA |
| 6(D285G)– | 0.16 | 6.2 | 12.5 | >1,000 |
| 6(D285G)+ | 0.16 | 3.1 | 3.1 | NA |
NA, not available.
