TABLE 1.
Genes coding for enzymes of the EMCP and the GC in Rhodobacter sphaeroides 2.4.1 and Escherichia coli K-12, respectively, and their homologues identified in P. denitrificans Pd1222a
Pathway or cycle |
Enzyme | Gene name |
Gene ID in: |
||
---|---|---|---|---|---|
R. sphaeroides
2.4.1 |
E. coli K-12 |
P. denitrificans Pd1222 |
|||
EMCP | β-Kethothiolase | phaA | RSP_0745 | – | Pden_2026 |
Acetoacetyl-CoA reductase | phaB | RSP_0747 | – | Pden_2027 | |
Crotonyl-CoA carboxylase/reductase | ccr | RSP_0960 | – | Pden_3873 | |
Ethylmalonyl-CoA/methylmalonyl-CoA epimerase | epi | RSP_0812 | – | Pden_2178 | |
Ethylmalonyl-CoA mutase | ecm | RSP_0961 | – | Pden_3875 | |
(2S)-Methylsuccinyl–CoA dehydrogenase | mcd | RSP_1679 | – | Pden_2840 | |
Mesaconyl-CoA hydratase | mch | RSP_0973 | – | Pden_0566 | |
β-Methylmalyl–CoA/l-malyl–CoA lyase | mcl-1 | RSP_1771 | – | Pden_0799 | |
(S)-Malyl–CoA thioesterase | mcl-2 | RSP_0970 | – | Pden_0563 | |
Propionyl-CoA carboxylase | pccAB | RSP_2191/2189 | – | Pden_3684/3688 | |
Ethylmalonyl-CoA/methylmalonyl-CoA epimerase | epi | RSP_0812 | – | Pden_2178 | |
(2R)-Methylmalonyl–CoA mutase | mcm | RSP_2912 | – | Pden_3681 | |
GC | Isocitrate lyase | aceA | – | C5Y66_09370 | Pden_1363 |
Malate synthase | aceB | – | C5Y66_09365 | Pden_1364 |
Key enzymes of the two pathways are in bold. Missing enzyme homologues are indicated by dashes.