Table 1.
Outcome measure/measurement | Minimal clinically important difference*/established cut-point | Study target for improvement in outcome score |
Godin Leisure-Time Questionnaire | 10% change in physical activity behaviour at 1 year | +10% or more of survivors are engaging in >150 min of moderate intensity physical activity at 1 year |
Waist circumference | Cut-points for health64: Men: 102 cm Women: 88 cm |
+10% survivors with reduction to below disease risk cut-point based on age and gender |
6 min walk test distance | 24 to 30.5 m65 | +30 m |
Hand-grip dynamometry | 6.5 kg66 67 | +10% meeting or exceeding age-specific average score |
30 s sit-to-stand | Not established in cancer | +10% in the number of participants meeting age-specific functional level |
Shoulder Flexion Range Goniometry |
>10 degrees68 | +10% meeting or exceeding age-specific average score |
Sit and reach test | Population values67 69
Men 0 to +5 cm Women 0 to +10 cm |
+10% meeting or exceeding age-specific average score |
Single leg balance: | 24 s70 | +10% meeting 45 s maximum time |
One repetition maximum test | MCID: 1%–3% | +10% increase |
Functional Assessment of Cancer Therapy (FACT)—General Scale | Population value46: score 88 MCID: 3 points |
+3 points |
FACT-Fatigue subscale | Population value47: score of 40 MCID: 3–6 points |
+6 points |
RAND Short Form-36 | Population value71: 67–87/100 across domains; MCID 6–7 points |
12% change from baseline |
EQ5D-5 L | EQ5D index: 0.0649 72 73 | +0.06 from baseline |
Attendance at sessions | Population values in older adults: 58% to 77%74 |
>70% attendance at exercise sessions |
*The minimum clinically important difference (MCID) is the minimum difference that the patient is able to recognise and appreciate.75