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. Author manuscript; available in PMC: 2019 Sep 17.
Published in final edited form as: Am J Perinatol. 2017 Nov 13;35(5):455–462. doi: 10.1055/s-0037-1608677

Table 2.

Pearson product moment correlations for serum cytokines across pregnancy

Systemic Cytokines First Trimester

N 288 288 288 288 288 288 288 205

IL-1α IL-1β IL-6 IL-8 IL-10 TNFα CRP MMP-8

IL-1α 1 .70** .57** .47** .43** .43** −.02 .25**
IL-1β 1 .57** .45** .47** .50** −.003 .28**
IL-6 1 .59** .51** .49** −.02 .07
IL-8 1 .33** .34** −.02 .19*
IL-10 1 .29** .12* −.03
TNFα 1 −.01 .15*
CRP 1 .18*
MMP-8 1

Second Trimester

N 243 243 243 243 243 243 243 170

IL-1α 1 .63** .58** .46** .45** .38** −.04 .27**
IL-1β 1 .56** .48** .43** .43** −.13* .32**
IL-6 1 .67** .49** .45** −.11 .15*
IL-8 1 .36** .48** −.17* .29**
IL-10 1 .33** .04 .08
TNFα 1 −.08 .18*
CRP 1 −.003
MMP-8 1

Third Trimester

N 221 221 221 221 221 221 221 152

IL-1α 1 .63** .58** .35** .49** .40** −.11 .07
IL-1β 1 .59** .51** .49** .39** −.13 .10
IL-6 1 .62** .53** .46** −.07 .08
IL-8 1 .32** .36** −.12 .26*
IL-10 1 .34** .02 .13
TNFα 1 −.04 .15
CRP 1 −.02
MMP-8 1

Note:

**

P < 0.001

*

P < 0.05