Fig. 2.
PdgfraCre/ERT drives tamoxifen induced Cre recombination to the peri-cloaca and genital tubercle mesenchyme in mice. Tamoxifen was given to pregnant mice at E9.5 and E10.5, embryos were collected at E11.5 (a, b) or at E14.5 (c, d) for X-gal staining and sectioning. Strong X-gal staining was only observed in R26R; PdgfraCre/ERT embryos but not in R26R embryos. Region highlighted was shown underneath. cl cloaca, gt genital tubercle, u ureter, urs urorectal septum, up urethral plate, uf urogenital fold, agm apical genital mesenchyme, t tail. n = number of embryos analyzed