Fig. 6.

Tbx1 inhibition did not affect myogenic cell self-renewal in TA-muscle-derived myoblasts in vivo. a Three weeks after transplantation (1 × 10⁵ cells/mouse), cross-sections of engrafted TA muscles were stained against GFP and laminin-α2, and the number of GFP(+) fibers was quantified. Values are presented as mean ± SE (n = 4). Scale bar = 100 µm. b Cross-sections of transplanted TA muscles stained against GFP, Pax7, and laminin-α2. Values are presented as mean ± SE (n = 4). Scale bar = 50 µm. c Two weeks after the second CTX injection, the transplanted muscles were dissected and cross-sections were stained against GFP and laminin-α2. Values are presented as mean ± SE (n = 4). Scale bar = 100 µm. d A model for the regulation of muscle fiber type and myogenic cell potential involving Tbx1