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. 2019 Sep 10;13:945. doi: 10.3389/fnins.2019.00945

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Copyright © 2019 Vagni, Perlini, Chenais, Marchetti, Parrini, Contestabile, Cancedda and Ghezzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Optomotor reflex upon electroporation at P8. (A) Mean (±SEM) visual acuity in Rd10 mice treated at P8 (Rd10 LT; treated eye 0.29 ± 0.01 C/°, untreated eye 0.19 ± 0.02 C/°; n = 7, p < 0.01, unpaired t-test). (B) Mean (±SEM) visual acuity in Rd10 mice treated at P3 and P8 (Rd10 ELT; treated eye 0.26 ± 0.01 C/°, untreated eye 0.16 ± 0.01 C/°; n = 28, p < 0.0001, unpaired t-test). (C) Mean (±SEM) visual acuity in Rd10 mice sham treated at P3 and P8 (Rd10 ELS; sham eye 0.13 ± 0.02 C/°, untreated eye 0.13 ± 0.02 C/°; n = 11, p = 0.8992, unpaired t-test).