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. 2019 Sep 10;12:215. doi: 10.3389/fnmol.2019.00215

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Copyright © 2019 Wang, Liao, Li, Chen and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokine detection by ELISA and cell viability assay by CCK-8. TUG1 knockdown suppressed the production of tumor necrosis factor-α (TNF-α; A) and interleukin-6 (IL-6; B) while elevated the concentration of interleukin-10 (IL-10; C) after OGD, with enhanced SH-SY5Y cell viability after OGD (D). The effects of TUG1 knockdown on inflammatory cytokines and cell survival were abolished by miR-145a-5p inhibitor. *P < 0.05 vs. the corresponding control. n = 4.