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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2019 Aug 12;380:114709. doi: 10.1016/j.taap.2019.114709

Fig. 5.

Fig. 5.

In vivo estrogenic activity of bisphenols in the cyp19a1b-GFP zebrafish. A. Concentration-dependent induction of GFP by BPA, BPAF and BPC in cyp19a1b-GFP transgenic larvae after exposure to the bisphenols from 0 to 4 dpf. Values are expressed as mean +/− SEM (n = 4–13). B. Effect of BPA, BPAF and BPC on EE2-mediated GFP induction in cyp19a1b-GFP transgenic larva after exposure from 0 to 4 dpf. Values are expressed as mean +/− SEM (n = 8–14). C. Fluorescence images of cyp19a1b-GFP transgenic larvae treated with 0.05 nM EE2, 10 μM BPA, 1 μM BPAF and 1 μM BPC alone and co-treatments of EE2 with the bisphenols. Images were taken in the dorsal view, anterior side to the top.