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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2019 Aug 12;380:114709. doi: 10.1016/j.taap.2019.114709

Table 2.

Dissociation constant (Kd) values for E2, 16α-LE2, BPA, BPAF and BPC on the zfERs. Values are the mean ± standard deviations from three separate experiments.

zfERα) zfERβ1 zfERβ2
Ligands Kd (nM) Kd (nM) Kd (nM)
E2 2.6 ± 0.6 1.1 ± 0.2 2.6 ± 0.7
16α-LE2 9.4 ± 0.9 1109 ± 126 351 ± 44
BPA 1245 ± 265 10040 ± 2919 6884 ± 1270
BPAF 428 ± 85 1023 ± 184 1993 ± 628
BPC 78 ± 16 678 ± 124 402 ± 89