Figure 12.

Potential future applications that take advantage of nucleic acid barcoding and NGS. a) mRNA-displayed cyclic peptide libraries can be delivered to cells using cationic lipids to enable cell-based screening assays. b) Barcoded nucleic acid-based sensors can be used in an endonuclease protection assay to facilitate detection and quantification of analytes. By implementing NGS as a readout, parallel analysis of multiple sensors is possible. c) A method for appending nucleic acid barcodes to proteins in live cells would allow for highly sensitive detection and reliable quantification of endogenous proteins.