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Chemical functionalities for labeling of natural and unnatural amino acid side chains with DNA barcodes. a) Lysine side chain labeling via an NHS-ester-DNA conjugate. b) Cysteine side chain labeling via a maleimide-DNA conjugate. c) Tyrosine side chain labeling via a cyclic diazodicarboxamide-DNA conjugate. d) p-acetylphenylalanine side chain labeling via an aminooxy-DNA conjugate.
