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. 2019 Sep 17;2019(9):CD003248. doi: 10.1002/14651858.CD003248.pub4

Comparison 9. DCC with immediate neonatal care after cord clamping vs ECC (low risk of bias).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death of baby (up to discharge) 5 1804 Risk Ratio (M‐H, Random, 95% CI) 0.71 [0.51, 0.97]
2 Death or neurodevelopmental impairment in early years 0 0 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
3 Severe intraventricular haemorrhage (IVH grades 3, 4) 4 1689 Risk Ratio (M‐H, Random, 95% CI) 0.84 [0.54, 1.32]
4 Intraventricular haemorrhage (IVH, all grades) 4 1689 Risk Ratio (M‐H, Random, 95% CI) 0.78 [0.52, 1.18]
5 Periventricular leukomalacia (PVL) 2 1448 Risk Ratio (M‐H, Random, 95% CI) 0.52 [0.23, 1.19]
6 Chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks (corrected for gestation) 4 1587 Risk Ratio (M‐H, Random, 95% CI) 1.05 [0.95, 1.15]
7 Maternal blood loss of 500 mL or greater 1 86 Risk Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]